I don’t see how LossLess has anything to do with Zwangsen. It is a completely independent app that doesn’t touch or interfere with the TSC code. My guess is that you are pressing Wachsam too early (or too late).
I haven’t had one single thing (including pzb) not functioning in TSC in the two days i’ve used LossLess.
I'd say so too, hence that I checked without pressing at all: When using x2, the Zwangse came immediately at the signal, at x3 it took 4 seconds (as it should). Curious, but true
EDIT: I've deactivated and reactivated Vulkan, and now everything seems normal, also using x2. Sometimes...